Complete list of genes tested —
For the latest list of conditions click here
Gene Cancers
AIP Pituitary adenomas
APC Colorectal, endocrine, gastric, nervous system/brain, and pancreatic cancer, sarcoma
ATM Breast, pancreatic, and prostate cancer
AXIN2 Colorectal cancer
BAP1 Renal/urinary tract cancer, melanoma
BARD1 Breast cancer
BMPR1A Colorectal, gastric, and pancreatic cancer
BRCA1 Breast, gynecologic, pancreatic, and prostate cancer
BRCA2 Breast, gynecologic, pancreatic, and prostate cancer, melanoma
BRIP1 Breast and gynecologic cancer
CDC73 Endocrine and renal/urinary tract cancer
CDH1 Breast, colorectal, and gastric cancer
CDK4 Melanoma
CDKN1B Prostate
CDKN2A Nervous system/brain and pancreatic cancer, melanoma
CHEK2 Breast, colorectal, endocrine, gynecologic, and prostate cancer
DICER1 Endocrine, gynecologic, nervous system/brain, and renal/urinary tract cancer, sarcoma
EGFR Lung cancer
EPCAM Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer
FH Renal/urinary tract cancer, sarcoma
FLCN Renal/urinary tract cancer
GREM1 Colorectal cancer
HOXB13 Prostate cancer
KIT Gastric cancer, sarcoma
LZTR1 Schwannomatosis
MAX Endorcrine cancer
MEN1 Endocrine, nervous system/brain, and pancreatic cancer
MET Renal/urinary tract cancer
MITF Melanoma
MLH1 Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer
MSH2 Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer
MSH3 Colorectal cancer, includes reporting of carrier status
MSH6 Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer
MUTYH Colorectal cancer
NF1 Breast, endocrine, gastric, and nervous system/brain cancer
NF2 Nervous system/brain cancer
NTHL1 Colorectal cancer, includes reporting of carrier status
PALB2 Breast and pancreatic cancer
PDGFRA Gastric cancer, sarcoma
PMS2 Colorectal, gastric, gynecologic, nervous system/brain, pancreatic, prostate, and renal/urinary tract cancer
POLD1 Colorectal cancer
POLE Colorectal cancer
POT1 Melanoma, leukaemia
PRKAR1A Endocrine and nervous system/brain cancer, sarcoma
PTCH1 Nervous system/brain and skin cancer, sarcoma
PTEN Breast, colorectal, endocrine, gynecologic, nervous system/brain and, renal/urinary tract cancer, melanoma
RAD51C Breast and gynecologic cancer
RAD51D Breast and gynecologic cancer
RB1 Melanoma, retinoblastoma, sarcoma
RET Endocrine cancer
SDHA Endocrine and gastric cancer, sarcoma
SDHAF2 Endocrine cancer
SDHB Endocrine, gastric, and renal/urinary tract cancer, sarcoma
SDHC Endocrine, gastric, and renal/urinary tract cancer, sarcoma
SDHD Endocrine, gastric, and renal/urinary tract cancer, sarcoma
SMAD4 Colorectal, gastric, and pancreatic cancer
SMARCA4 Gynecologic cancer
SMARCB1 Nervous system/brain and renal/urinary tract cancer
STK11 Breast, colorectal, gastric, gynecologic, and pancreatic cancer
TMEM127 Endocrine cancer
TP53 Breast, endocrine, gastrointestinal, genitourinary, gynecologic, hematologic, nervous system/brain, and skin cancer, sarcoma
TSC1 Nervous system/brain, pancreatic, and renal/urinary tract cancer
TSC2 Nervous system/brain, pancreatic, and renal/urinary tract cancer
VHL Endocrine, nervous system/brain, pancreatic, and renal/urinary tract cancer
WT1 Renal/urinary tract cancer